Author

Alix Schwiening

AstraZeneca (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:scRNA-seq· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Anca M. FarcasiD· 1 shared Andrei ProdaniD· 1 shared Christine RowleyiD· 1 shared Dean Swinden· 1 shared Deborah Kronenberg‐VersteegiD· 1 shared Dmytro ShepiloviD· 1 shared Doreth Fransen· 1 shared Dylan MooijmaniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Anca M. FarcasORCID

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2 papers

Recent·Most cited

10x Genomics Gene Expression Flex is a powerful tool for single-cell transcriptomics of xenograft models

Oriol Llorà-Batlle, Anca M. Farcas, Doreth Fransen, Nicolas Floc’h, Sara Talbot, Alix Schwiening, Laura Bojko, John Calver, Nataša Josipović, Kanstantsin Lashuk, Julia B. Schüler, Andrei Prodan, Dylan Mooijman, Ultan McDermott

The paper demonstrates that the 10x Genomics Gene Expression Flex protocol can profile mixed human and mouse cells in xenografts by using combined probe sets and a pipeline to remove cross-reactive signals.

bioRxiv · Jan 25, 2024 · PreprintGenomics

Metformin acts directly in the brain to slow features of neurodegeneration.

Edward C. Harding, Hsiao‐Jou Cortina Chen, Dmytro Shepilov, Marc Welzer, Viviana Macarelli, Alix Schwiening, Christine Rowley, Sanya Aggarwal, Dean Swinden, Deborah Kronenberg‐Versteeg, Florian T. Merkle

This study shows metformin can slow neurodegeneration features in mice, even in metabolically healthy individuals, by acting directly in the brain.

bioRxiv · Jul 18, 2023 · PreprintNeuroscience