Rationally Designed PKD1 Activator Protects Against Neurodegeneration in Pre-clinical Models of Parkinson's Disease
Arunkumar Asaithambi, Ah-Young Jang, Anamitra Ghosh, Muhammet Ay, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy
The paper develops a rationally designed PKD1 activator peptide, AK-P4T, which protects against neurodegeneration in pre-clinical Parkinson's disease models.
bioRxiv · Feb 13, 2025 · PreprintNeuroscience