Nicholas J. C. King

High fat low carbohydrate diet is linked to protection against CNS autoimmunity

This study links a high fat low carbohydrate diet to protection against CNS autoimmunity by showing reduced neuroinflammation and immunometabolic changes in a mouse model.

Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes

This study shows that mice lacking CerS2 in oligodendrocytes develop myelin instability, microglial activation, and early lethality due to reduced C22-C24 sphingolipids.

TrackSOM: mapping immune response dynamics through sequential clustering of time- and disease-course single-cell cytometry data

TrackSOM maps immune response dynamics through sequential clustering of time- and disease-course single-cell cytometry data, revealing heterogeneous immune cell populations and their functional evolution in West Nile Virus infection.