Targeted gene correction and functional recovery in achondroplasia patient-derived iPSCs
Huan Zou, Mingfeng Guan, Yundong Li, Fang Luo, Wenyuan Wang, Yiren Qin
This study corrects a mutation in achondroplasia patient-derived iPSCs using CRISPR-Cas9 and restores their chondrogenic differentiation ability.
bioRxiv · Sep 2, 2020 · PreprintDevelopmental Biology