Author

Mingfeng Guan

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Wenyuan WangiD· 3 shared Congcong Xia· 2 shared Fang LuoiD· 2 shared Guoming MaiD· 2 shared Jie LiuiD· 2 shared Boyu LyuiD· 1 shared Changyin YuiD· 1 shared Gang PeiiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Wenyuan WangORCID

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3 papers

Recent·Most cited

Astrocyte-specific secretome profiling reveals its correlation with neurological disorders

Jie Liu, Jing Gao, Lin Guo, Guoming Ma, Mingfeng Guan, Congcong Xia, Jia He, Yufang Yang, Yi Wu, Jun Xu, Liuling Xiong, Changyin Yu, Gang Pei, Jian Zhao, Jianchen He, , Wenyuan Wang

The paper develops a secretome profiling method for astrocytes and identifies proteins involved in disease-related toxicity and neuroprotection.

bioRxiv · Nov 21, 2024 · PreprintNeuroscience

Integrated temporal profiling of iPSCs-derived motor neurons from ALS patients carrying C9orf72, FUS, TARDBP, and SOD1 mutations

Guoming Ma, Congcong Xia, Boyu Lyu, Jie Liu, Fang Luo, Mingfeng Guan, Junying Wang, Li Sun, Lin Zhang, Yan Chen, Yingwei Mao, Guoqiang Yu, Wenyuan Wang

This study profiles temporal RNA-seq in iPSC-derived motor neurons from ALS patients with specific mutations, identifying shared gene expression and splicing defects across different mutations.

bioRxiv · Oct 15, 2024 · PreprintNeuroscience

Targeted gene correction and functional recovery in achondroplasia patient-derived iPSCs

Huan Zou, Mingfeng Guan, Yundong Li, Fang Luo, Wenyuan Wang, Yiren Qin

This study corrects a mutation in achondroplasia patient-derived iPSCs using CRISPR-Cas9 and restores their chondrogenic differentiation ability.

bioRxiv · Sep 2, 2020 · PreprintDevelopmental Biology