Christine L. Mac Donald

QNPtoVox maps 2D quantitative neuropathology data to 3D MNI voxel space for spatial standardization and integration with neuroimaging tools.

This paper shows that free water elimination improves tractometry reliability and accuracy in aging brains using a large cohort and provides open-source software for this technique.

This study creates an integrated multimodal cell atlas of Alzheimer's disease by analyzing single nuclei transcriptomes, epigenomes, and spatial coordinates across AD stages.

The paper develops open-source tools for 3D analysis of brain dissection photographs and surface scans, achieving accurate reconstructions and segmentations comparable to MRI.

This study uses ex vivo diffusion MRI and histopathology to correlate tract disruptions with axonal injury in a TBI patient.

This study compares DTI and NODDI biomarkers in mTBI patients to assess white matter changes over time and their association with cognitive recovery.

The paper identifies cognitive subgroups in Alzheimer's disease based on MRI-derived atrophy patterns and links them to specific biological pathways using transcriptomic data.

This study introduces a lesion correction method for cortical volumetric analysis in TBI patients, improving accuracy and enabling inclusion of lesioned brains in network-based analyses.