Xue Cai

This study uses population-based metaproteomics to identify functional associations between gut microbiota and 39 phenotypes, including 1,381 features related to Type 2 Diabetes.

metaExpertPro constructs metaproteomics spectral libraries and analyzes DIA-MS data, achieving high peptide quantification and low FDR in human fecal samples.

DPHL v2 improves upon DPHL v1 by including semi-tryptic peptides and protein isoforms, increasing identified and dysregulated proteins in colorectal cancer analysis.

The paper constructs a comprehensive mass spectral library for human thyroid tissues to improve the detection of malignant nodules through proteomic analysis.

The paper introduces DPHL, a pan-human protein mass spectrometry library built using DIA and PRM, and demonstrates its utility in identifying differentially expressed proteins in prostate cancer and DLBCL.