Lukasz Smigielski

Ensemblex improves accuracy in genetic demultiplexing of pooled scRNA-seq samples by combining four algorithms with accuracy weighting.

The paper identifies amacrine cells as enriched in schizophrenia genetic risk and links this to synaptic biology, while finding retinal immune cells associated with multiple sclerosis.

This study links genetic risk for schizophrenia with retinal thinning using UK Biobank data, highlighting neuroinflammatory pathways as a potential mechanism.

This study examines brain morphometric deviations in individuals at clinical high-risk for psychosis and finds they largely overlap with healthy variation and are not strongly associated with symptom severity or conversion to psychosis.

The paper examines how reactive and proactive aggression subtypes relate to distinct resting state functional connectivity patterns in children and adolescents with disruptive behavior.

The paper examines functional connectivity differences in children and adolescents with disruptive behavior, finding distinct patterns for reactive and proactive aggression and callous-unemotional traits, emphasizing the role of comorbid symptoms.