Binding to nucleosome poises human SIRT6 for histone H3 deacetylation
Ekaterina Smirnova, Emmanuelle Bignon, Patrick Schultz, Gábor Pápai, Adam Ben Shem
This study reveals how SIRT6 binds to nucleosomes to position its active site for efficient histone H3 deacetylation.
eLife · Jun 2, 2023Peer-reviewedMolecular Biology