Arnav A. Gupta

The paper identifies airway epithelial transcriptional mechanisms linked to air pollutant exposure and lung disease risk using a functional genomics pipeline, highlighting hyaluronic acid metabolism and TOMM7 regulation as potential therapeutic targets.

The paper uses ATAC-seq and PRO-seq to study transcriptional and epigenetic responses to Afghan desert particulate matter in human small airway epithelial cells, identifying key pathways and transcription factors involved.

The paper uses genomics techniques to analyze transcriptional responses to wood smoke particles and identifies rapid AHR signaling dynamics and interactions with NFkB.

The paper uses GRO-seq to show glucocorticoids rapidly repress transcription without local GR occupancy and induce anti-inflammatory effects through GR-NF-kB cooperation.