This study uses CRISPR/Cas12a to target and cleave Wheat Dwarf Virus genomes without genetic modification, showing effective antiviral activity in vitro.

Tarım Bilimleri Dergisi · Mar 24, 2026Peer-reviewedPlant Biology

Autonomous Remotely Controlled Closed System Transgenic Cell Technologies Robot: CRISPR.BOT

Fatmanur Erkek, Gamze Gülden, Berranur Sert, Menekse Cagla Yilmaz, Sibel Pınar Odabaş, Enes Bal, Gamze Yelgen, Tarık Teymur, Yasin Ay, Solen Dogdu, Nulifer Neslihan Tiryaki, Buse Baran, Beste Gelsin, Hasret Araz, Ilayda Cavrar, Cihan Taştan

This paper introduces CRISPR.BOT, a robotic system for automated genetic engineering tasks, achieving high-purity single-cell subcloning and reducing labor and costs in biosafety level 3 experiments.

bioRxiv · Jul 22, 2022 · PreprintMolecular Biology

Exon7 Targeted CRISPR-Prime Editing Approaches for SMN2 Gene Editing in Spinal Muscular Atrophy (SMA) Disease Can Increase In Vitro SMN Expression

Sibel Pınar Odabaş, Enes Bal, Gamze Yelgen, Ayse Simay Metin, Ebrar Karakaya, Gamze Gülden, Berranur Sert, Tarık Teymur, Yasin Ay, Nulifer Neslihan Tiryaki, Hasret Araz, Ilayda Cavrar, Cihan Taştan

This study uses CRISPR-Prime Editing to correct two point mutations in the SMN2 gene, increasing SMN expression in SMA-related cells.

bioRxiv · Mar 21, 2022 · PreprintGenetics