Lipodystrophy and recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis.
Suneeti R. Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Michael C. Rudolph, Radhika P. Atit
This study shows that the Wnt/lipogenesis axis mediates lipodystrophy and recovery in skin fibrosis by regulating lipid content and extracellular matrix.
bioRxiv · Sep 24, 2025 · PreprintCell Biology