Reshmi Parameswaran

B-cell activating factor plays a critical role in CAR-T cell-associated cytokine release syndrome

This study identifies BAFF as a key mediator of CAR-T cell-related cytokine release syndrome and shows that neutralizing BAFF reduces cytokine production without affecting CAR-T cell function.

Lipodystrophy and recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis.

This study shows that the Wnt/lipogenesis axis mediates lipodystrophy and recovery in skin fibrosis by regulating lipid content and extracellular matrix.