Comparative study of Ergosterol and 7-dehydrocholesterol and their Endoperoxides: Generation, Identification and Impact in Phospholipid Membranes and Melanoma Cells
Megumi Nishitani Yukuyama, Karen Campos Fabiano, Alex Inague, Miriam Uemi, Rodrigo Santiago Lima, Larissa Regina Diniz, Tiago E. Oliveira, Thais Satie Iijima, Hector Oreliana Fernandes Faria, Rosângela Silva Santos, Maria Fernanda Valente Nolf, Adriano B. Chaves‐Filho, Marcos Yukio Yoshinaga, Helena C. Junqueira, Paolo Di Mascio, , Sayuri Miyamoto
This study compares the effects of ergosterol, 7-dehydrocholesterol, and cholesterol under oxidative stress in melanoma cells, showing endoperoxides from these sterols are more effective in reducing cell viability.
Photochemistry and Photobiology · Jan 21, 2025Peer-reviewedBiochemistry