Author

Marcos Yukio Yoshinaga

Universidade Cruzeiro do SulORCID 0000-0002-5533-5348Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:metabolomics· 3 Research Focus:differential expression· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Sayuri MiyamotoiD· 3 shared Adriano B. Chaves‐FilhoiD· 2 shared Tiago E. OliveiraiD· 2 shared Álbert S. PeixotoiD· 1 shared Alex InagueiD· 1 shared Alicia Juliana KowaltowskiiD· 1 shared Ana B. PiresiD· 1 shared Andrei Carvalho SpositoiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

Sayuri MiyamotoORCID

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4 papers

Recent·Most cited

Constitutive PI3K-AKT activation promotes steatohepatitis through de novo lipogenesis despite enhanced mitochondrial β-oxidation, essential fatty acid depletion and reduced lipid peroxidation

Álbert S. Peixoto, Érique Castro, Bianca Franco Leonardi, Tiago E. Oliveira, Adriano B. Chaves‐Filho, Thayna S. Vieira, Caroline Aparecida Tomazelli, Natália Monteiro Pessoa, Érika Vicência Monteiro Pessoa, Marina A. Abe‐Honda, Ana B. Pires, Luciano Pedro da Silva, Erick M. Silveira, Beatriz Pereira da Silva, Camila Nogueira Alves Bezerra, , William T. Festuccia

bioRxiv · Sep 24, 2026 · PreprintBiochemistry

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Débora Santos Rocha, Eloisa Aparecida Vilas‐Boas, Camille C. Caldeira da Silva, Éverton Lopes Vogt, Marcos Yukio Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia Juliana Kowaltowski

This study shows that ERβ activation with DPN improves metabolic outcomes in postmenopausal rats by remodeling liver lipid metabolism and enhancing ketone body production.

Comprehensive physiology · Jul 19, 2026Peer-reviewedBiochemistry

Cold acclimation reprograms hepatic lipid composition toward n-3 HUFAs to uncouple adipose-derived lipid flux from steatosis

Victor Azevêdo Vieira, Gabriel Salerno Costa, Gabriela Segura Gonzales, Raphael Campos Guimarães, Cristiane dos Santos, Raul Gobato da Costa, Marcella Ramos Sant'Ana, Camila de Oliveira Ramos, Murilo Henrique Anzolini Cassiano, João Manoel Alves, Nayara Fernanda Pereira, Paulo Henrique Melo, Tiago Tomazini Gonçalves, Isabella Bonilha, Caio Fábio Baeta Lopes, , Luiz Osório Leiria

The paper shows cold acclimation increases n-3 HUFAs in the liver, reducing steatosis by altering lipid composition and metabolism.

bioRxiv · Mar 31, 2026 · PreprintBiochemistry

Comparative study of Ergosterol and 7-dehydrocholesterol and their Endoperoxides: Generation, Identification and Impact in Phospholipid Membranes and Melanoma Cells

Megumi Nishitani Yukuyama, Karen Campos Fabiano, Alex Inague, Miriam Uemi, Rodrigo Santiago Lima, Larissa Regina Diniz, Tiago E. Oliveira, Thais Satie Iijima, Hector Oreliana Fernandes Faria, Rosângela Silva Santos, Maria Fernanda Valente Nolf, Adriano B. Chaves‐Filho, Marcos Yukio Yoshinaga, Helena C. Junqueira, Paolo Di Mascio, , Sayuri Miyamoto

This study compares the effects of ergosterol, 7-dehydrocholesterol, and cholesterol under oxidative stress in melanoma cells, showing endoperoxides from these sterols are more effective in reducing cell viability.

Photochemistry and Photobiology · Jan 21, 2025Peer-reviewedBiochemistry