Author

Daniel Seehofer

University Hospital LeipzigORCID 0000-0002-7492-8309Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Georg DammiD· 4 shared Christiane KörneriD· 2 shared Jens TimmeriD· 2 shared Marcel SchillingiD· 2 shared Ursula KlingmülleriD· 2 shared Agnieska BrazovskajaiD· 1 shared Ahmed GhallabiD· 1 shared Andrea ScheffschickiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersSystems Biology

Georg DammORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintJan 21, 2025

CD271 sorting for improved liver cell isolation: Semiautomated and simultaneous preparation of parenchymal and non-parenchymal cells from mouse and human livers

Anne Dropmann, Bedair Dewidar, Kerry Gould…·Seddik Hammad

This paper introduces a semi-automated protocol for isolating multiple liver cell types from mouse and human livers with high yield, purity, and viability.

DOI 10.1101/2025.01.21.633876

mousehuman

𝕏 PostBluesky

Systems BiologyMolecular Systems BiologyPeer-reviewedJan 12, 2024

Basal MET Phosphorylation is an Indicator of Hepatocyte Dysregulation in Liver Disease

Sebastian Burbano de Lara, Svenja Kemmer, Ina Biermayer…·Ursula Klingmüller

The paper identifies elevated basal MET phosphorylation as a marker of hepatocyte dysregulation in liver disease, correlating with patient outcomes after surgery.

10 citations

humanproteomics

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GenomicsbioRxivPreprintJun 3, 2021

Cell atlas of the regenerating human liver after portal vein embolization

Agnieska Brazovskaja, Tomás Gomes, Christiane Körner…·Barbara Treutlein

This study uses single-cell transcriptomics to analyze liver regeneration after portal vein embolization, identifying changes in cell states and immune interactions.

6 citations

humanscRNA-seq

𝕏 PostBluesky

Systems BiologyPLoS PathogensPeer-reviewedOct 1, 2020

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

Katharina Robichon, Tim Maiwald, Marcel Schilling…·Ursula Klingmüller

This study identifies IL1β as an amplifier of IFN-induced antiviral responses through mathematical modeling and experimental validation.

9 citations

mousestatistical model

𝕏 PostBluesky