Author

Nicole C. Gadda

University of North Carolina at Chapel HillORCID 0000-0002-7493-8136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Jilarie A. Santos-SantiagoiD· 1 shared Rani S. SellersiD· 1 shared Rita TamayoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperMicrobiology

Jilarie A. Santos-SantiagoORCID

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1 paper

Recent·Most cited

MicrobiologyInfection and ImmunityPeer-reviewedJun 9, 2026

Phase variable colony morphotypes of Clostridioides difficile elicit distinct host responses during acute infection

Jilarie A. Santos-Santiago, Nicole C. Gadda, Rani S. Sellers, Rita Tamayo

This study compares the host immune response and fitness of rough and smooth colony morphotypes of C. difficile during infection, finding that rough colonies elicit stronger immune responses but lower fitness.

1 citation

mouseexperimental assay

𝕏 PostBluesky