Author

Jilarie A. Santos-Santiago

University of North Carolina at Chapel HillORCID 0000-0002-1328-0174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Rita TamayoiD· 2 shared Alexander B. SmithiD· 1 shared Ashley S. WeissiD· 1 shared Joseph P. ZackulariD· 1 shared Montana KnightiD· 1 shared Nicole C. GaddaiD· 1 shared Orlaith KeenaniD· 1 shared Rani S. SellersiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

Rita TamayoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Phase variable colony morphotypes of Clostridioides difficile elicit distinct host responses during acute infection

Jilarie A. Santos-Santiago, Nicole C. Gadda, Rani S. Sellers, Rita Tamayo

This study compares the host immune response and fitness of rough and smooth colony morphotypes of C. difficile during infection, finding that rough colonies elicit stronger immune responses but lower fitness.

Infection and Immunity · Jun 9, 2026Peer-reviewedMicrobiology

Enterococcus faecalis modulates phase variation in Clostridioides difficile

Ashley S. Weiss, Jilarie A. Santos-Santiago, Orlaith Keenan, Alexander B. Smith, Montana Knight, Joseph P. Zackular, Rita Tamayo

This study shows Enterococcus faecalis influences phase variation in Clostridioides difficile, altering its phenotypes through the CmrRST system.

Journal of Bacteriology · Dec 23, 2025Peer-reviewedMicrobiology