Author

Matthijs Van Der Heyden

KU LeuvenORCID 0000-0002-7501-7195Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ben FabryiD· 1 shared Dorothea SchultheisiD· 1 shared Harald O. HerrmanniD· 1 shared Jan-Philipp BurchertiD· 1 shared Lovis SchweeniD· 1 shared Norbert MückeiD· 1 shared Sarah KösteriD· 1 shared Sergei V. StrelkoviD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Ben FabryORCID

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1 paper

Recent·Most cited

Desmin Mutations Disrupt Filament Elongation and Drive Polymorphic Aggregation

Lovis Schween, Jan-Philipp Burchert, Matthijs Van Der Heyden, Dorothea Schultheis, Norbert Mücke, Sarah Köster, Sergei V. Strelkov, Harald O. Herrmann, Ben Fabry

This study examines how desmin mutations affect filament assembly and aggregation, finding that specific mutations disrupt filament maturation and lead to distinct aggregation pathways.

bioRxiv · Oct 31, 2026 · PreprintBiophysics