NeuroscienceAlzheimer s Research & TherapyPeer-reviewed
New insights into the 17β-hydroxysteroid dehydrogenase type 10 and amyloid-β 42 derived cytotoxicity relevant to Alzheimer's disease
Aneta Houfková, Monika Schmidt, Ondřej Benek…·Kamil Musílek
This study shows that HSD10 overexpression causes cytotoxicity linked to mitochondrial damage, and this effect is worsened by Aβ-rich environments, with inhibitors showing potential therapeutic benefit.
2 citations