Author

Dajun Sang

NYU Langone HealthORCID 0000-0002-7512-074XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

Liam J. HoltiD· 2 shared Benjamin Turk· 1 shared Hua Jane Lou· 1 shared Sezen Vatansever· 1 shared Sudarshan PinglayiD· 1 shared Tong ShuiD· 1 shared Zeynep H. Gümüş· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersSynthetic Biology

Liam J. HoltORCID

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2 papers

Recent·Most cited

Synthetic Condensed-Phase Signaling Expands Kinase Specificity and Responds to Macromolecular Crowding

Dajun Sang, Tong Shu, Liam J. Holt

The paper shows synthetic condensates enhance kinase activity and specificity, revealing principles of phosphorylation dynamics in response to macromolecular crowding.

bioRxiv · Dec 10, 2021 · PreprintSynthetic Biology

Ancestral resurrection reveals mechanisms of kinase regulatory evolution

Dajun Sang, Sudarshan Pinglay, Sezen Vatansever, Hua Jane Lou, Benjamin Turk, Zeynep H. Gümüş, Liam J. Holt

The paper uses ancestral resurrection to show that changes in the β3-C loop and gatekeeper residue in ERK kinases drove the evolution of lower intrinsic autophosphorylation.

bioRxiv · May 25, 2018 · PreprintEvolutionary Biology