Author
NYU Langone HealthORCID 0000-0001-6036-0057Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Margaret A. Elpers, Jacob Odell, Sarah J. Henretta…·Jan Lammerding
This study shows that pro-inflammatory polarization of macrophages increases nuclear stiffness despite reduced lamin A/C levels, suggesting chromatin changes drive nuclear mechanics.
Shriram Venkatesan, Alex T. Von Schulze, Jeffrey J. Lange…·Randal Halfmann
The paper shows that increasing translation initiation rates accelerates nucleation of aggregating proteins at polysomes, suggesting cotranslational nucleation influences proteome evolution.
Nora L. Herzog, Tong Shu, Gururaj Rao Kidiyoor…·Liam J. Holt
This study shows HSV-1 protein ICP4 increases nuclear fluidity to enable condensate formation, supporting viral replication.
Meta Heidenreich, Saurabh Mathur, Tong Shu…·Emmanuel D. Levy
The paper identifies 68 yeast genes that globally influence protein phase separation through genetic knockouts and synthetic biology.
Dajun Sang, Tong Shu, Liam J. Holt
The paper shows synthetic condensates enhance kinase activity and specificity, revealing principles of phosphorylation dynamics in response to macromolecular crowding.
Ramalingam Venkat Kalyana Sundaram, Huaizhou Jin, Feng Li…·Shyam Sundar Krishnakumar
The paper shows Munc13-1 directly binds SNAP25 to initiate SNARE complex assembly, using FRET and optical tweezer techniques.