Steven M. Offer

BEDwARS improves bulk gene expression deconvolution by estimating cell type proportions and signatures simultaneously, showing robustness to noisy references and identifying mechanisms in a rare pediatric condition.

The paper introduces AMAPEX, a method to label proximal proteins of post-translationally modified proteins using antibody-mediated protein A-APEX2 labeling, and validates it with histone modification profiling.