Author

Abbey J. Telfer

Diamond Light SourceORCID 0000-0002-7525-8052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Allen Milster OrvilleiD· 2 shared Anastasiia ShilovaiD· 2 shared Catherine L. TookeiD· 2 shared JAMES M. SPENCERiD· 2 shared Jos J. A. G. KampsiD· 2 shared Laura ParkinsoniD· 2 shared N. E. DevenishiD· 2 shared Philip HinchliffeiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Allen Milster OrvilleORCID

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2 papers

Recent·Most cited

Time-resolved ligand dynamics revealed in a β-lactamase using room-temperature serial crystallography

Philip Hinchliffe, Catherine L. Tooke, Michael Beer, Pierre Aller, Jos J. A. G. Kamps, Laura Parkinson, Tiankun Zhou, N. E. Devenish, Do-Heon Gu, Anastasya Shilova, Matthew J. Rodrigues, Abbey J. Telfer, Agata Butryn, Marko Hanževački, Emily I. Freeman, , JAMES M. SPENCER

This study uses room-temperature serial crystallography to observe time-dependent ligand dynamics of the β-lactamase CTX-M-15 with avibactam, revealing conformational changes critical for inhibitor reformation.

bioRxiv · Dec 19, 2025 · PreprintBiochemistry

Droplet on Demand Tape Drive and XES Prototypes for Time-Resolved Serial Crystallography at VMXi, Diamond Light Source

Pierre Aller, Juan Sánchez-Weatherby, Abbey J. Telfer, Robert Bosman, N. E. Devenish, Philip Hinchliffe, Sam Horrell, Jophy Ip, Richard Littlewood, Andrew Male, Eva Giminez Navarro, Urszula Neuman, Jos J. A. G. Kamps, David Omar, Laura Parkinson, , Allen Milster Orville

The paper demonstrates proof of concept for combined droplet on demand serial crystallography and XES experiments at a synchrotron beamline.

bioRxiv · Nov 19, 2025 · PreprintBiophysics