Neprilysin inhibition reduces microtubule detyrosination in cardiomyocytes through a cGMP-PRKG1-VASH1 axis
Moritz Meyer-Jens, Chadni Sanyal, Niels Pietsch…·Lucie Carrier
Author
University Medical Center Hamburg-EppendorfORCID 0000-0002-7529-5179Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Moritz Meyer-Jens, Chadni Sanyal, Niels Pietsch…·Lucie Carrier
Konstantin Hennis, Chiara Piantoni, Martina Orabona…·Christian Wahl‐Schott
This study investigates the roles of HCN1 and HCN4 in synchronizing sinoatrial pacemaker cells, finding HCN1 is essential for fast synchronisation while HCN4 is not.
Sabine Rebs, Farbod Sedaghat‐Hamedani, Elham Kayvanpour…·Katrin Streckfuß‐Bömeke
This study compares patient-specific stem cell models of RBM20 mutations causing dilated cardiomyopathy and left ventricular non-compaction, identifying distinct molecular, cellular, and functional impairments.
Claudia Carlantoni, Leon M.H. Liekfeld, Sandra A. Hemkemeyer…·Maike Frye
This study identifies PDE2A as a regulator of lymphatic endothelial development through cGMP-mediated control of Notch signaling, showing its role in junction maturation and cell cycle arrest.