CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunction
Natália Ferreira Mendes, Ariane Maria Zanesco, Cristhiane Fávero de Aguiar, Gabriela Flavia Rodrigues-Luiz, Dayana Cabral da Silva, Jonathan F. Campos, Niels Olsen Saraiva Câmara, Pedro M. Moraes‐Vieira, ELIANA PEREIRA DE ARAUJO, Licio Augusto Velloso
This study identifies transcriptional differences between resident and recruited hypothalamic microglia in diet-induced obesity, showing that CXCR3-expressing recruited cells protect against metabolic dysfunction.
bioRxiv · Jan 16, 2024Neuroscience