Pedro M. Moraes‐Vieira

E4BP4 Safeguards Brown Fat Mitochondria from Obesity-Induced Fragmentation via Ceramide Repression

This study identifies E4BP4 as a transcriptional repressor that prevents obesity-induced mitochondrial fragmentation in brown fat by inhibiting ceramide synthesis, improving glucose homeostasis without weight loss.

CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunction

This study identifies transcriptional differences between resident and recruited hypothalamic microglia in diet-induced obesity, showing that CXCR3-expressing recruited cells protect against metabolic dysfunction.

Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection

This study investigates how SARS-CoV-2 infection affects mitochondrial gene expression in different tissues and disease stages, finding targeted inhibition in some organs and upregulation in others.

The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection

The paper identifies miR-2392 as a miRNA involved in SARS-CoV-2 infection, showing its role in inflammation, glycolysis, and hypoxia, and develops a miRNA-based therapeutic targeting it.