Author

Rita C. Smith

University of ChicagoORCID 0000-0002-7546-5019Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Anitha SundararajaniD· 2 shared Ashley M. SidebottomiD· 2 shared Che Woodson· 2 shared David MoraniD· 2 shared Emma McSpadden· 2 shared Eric G. PameriD· 2 shared Huaiying LiniD· 2 shared Mary McMilliniD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Anitha SundararajanORCID

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2 papers

Recent·Most cited

Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain

Qiwen Dong, Stephen Harper, Emma McSpadden, Sophie S Son, Marie-Maude Allen, Huaiying Lin, Rita C. Smith, Carolyn K. Metcalfe, Victoria Burgo, Che Woodson, Anitha Sundararajan, Amber R. Rose, Mary McMillin, David Moran, Jessica Little, , Eric G. Pamer

This paper shows that an avirulent C. difficile strain, ST1-75, protects mice from virulent strain-induced colitis by outcompeting it through rapid amino acid depletion, suggesting potential as a biotherapeutic for CDI prevention.

Cell Host & Microbe · Nov 27, 2024Peer-reviewedMicrobiology

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

Zhenrun J. Zhang, Cody G. Cole, Michael J. Coyne, Huaiying Lin, Nicholas Dylla, Rita C. Smith, Téa E. Pappas, Shannon A. Townson, Nina Laliwala, Emily Waligurski, Ramanujam Ramaswamy, Che Woodson, Victoria Burgo, Jessica C. Little, David Moran, , Laurie E. Comstock

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

bioRxiv · Mar 8, 2024Microbiology