David Moran

This paper presents a rapid diagnostic test to measure fecal butyrate and deoxycholic acid concentrations as markers of microbiome function, enabling quick identification of patients with microbiome deficiencies.

This paper shows that an avirulent C. difficile strain, ST1-75, protects mice from virulent strain-induced colitis by outcompeting it through rapid amino acid depletion, suggesting potential as a biotherapeutic for CDI prevention.

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.