Author

Makoto Iwasaki

Osaka Metropolitan UniversityORCID 0000-0002-7564-157XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Organism:non-human primate· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Akihisa TerakitaiD· 2 shared Mitsumasa KOYANAGIiD· 2 shared Tomohiro Sugihara· 2 shared Yukiya Kakeyama· 2 shared Yusuke SakaiiD· 2 shared Akifumi Takaori‐KondoiD· 1 shared Akinori YodaiD· 1 shared Albin ÖsterroosiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

Akihisa TerakitaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Self-regenerating opsin from reef-building coral

Yusuke Sakai, Yasushi Imamoto, Shino Inukai, Yuri Tominaga, Tomohiro Sugihara, Takahiro Yamashita, Kota Katayama, Yukiya Kakeyama, Ririka Oka, Erika Okuno, Makoto Iwasaki, Hideki Kandori, Mitsumasa KOYANAGI, Akihisa Terakita

This paper identifies a coral opsin, AtAntho2c, that can autonomously regenerate its inactive state through thermal isomerization of retinal, enabling repeated light responses without exogenous retinal.

bioRxiv · May 28, 2026 · PreprintBiophysics

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukemia

Yotaro Ochi, Markus Liew-Littorin, Yasuhito Nannya, Sofia Bengtzén, Bénédicte Piauger, Stefan Deneberg, Martin Jädersten, Vladimir Lazarević, Jörg Cammenga, Anna Robelius, Lovisa Wennström, Emma Ölander, Senji Kasahara, Nobuhiro Hiramoto, Nobuhiro Kanemura, , Seishi Ogawa

This study identifies 16 AML subgroups based on chromatin accessibility profiles using ATAC-seq in 1,563 cases, revealing epigenetic heterogeneity and its clinical and therapeutic implications.

bioRxiv · May 24, 2026 · PreprintCancer Biology

Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning

Yusuke Sakai, Saumik Sen, Tomohiro Sugihara, Yukiya Kakeyama, Makoto Iwasaki, Gebhard F. X. Schertler, Xavier Deupí, Mitsumasa Koyanagi, Akihisa Terakita

This study identifies a novel chloride counterion mechanism in coral opsins that stabilizes the Schiff base proton, enabling light sensitivity without a traditional counterion residue.

bioRxiv · Dec 12, 2024 · PreprintBiophysics