Author

Joseph R. Scarpa

Icahn School of Medicine at Mount SinaiORCID 0000-0002-7596-9401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexander W. CharneyiD· 2 shared Brendan Sullivan· 2 shared Brian Harris KopelliD· 2 shared Claudia FengiD· 2 shared Emily MoyaiD· 2 shared Eric E. SchadtiD· 2 shared Eric VornholtiD· 2 shared Esther ChengiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Alexander W. CharneyORCID

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2 papers

Recent·Most cited

A study of gene expression in the living human brain

Lora E. Liharska, You Jeong Park, Kimia Ziafat, Lillian Wilkins, Hannah Silk, Lisa M. Linares, Ryan C. Thompson, Eric Vornholt, Brendan Sullivan, Vanessa V. Cohen, Prashant Kota, Claudia Feng, Esther Cheng, Jessica Johnson, Marysia-Kolbe Rieder, , Alexander W. Charney

This study compares gene expression in living and postmortem human brain tissue, finding significant differences that challenge the assumption that postmortem data accurately represents living brain gene expression.

Molecular Psychiatry · Aug 23, 2025Peer-reviewedGenetic & Genomic Medicine

Divergent landscapes of A-to-I editing in postmortem and living human brain

Miguel Rodríguez de los Santos, Brian Harris Kopell, Ariela Buxbaum Grice, Gauri Ganesh, Andy Yang, Pardis Amini, Lora E. Liharska, Eric Vornholt, John F. Fullard, Pengfei Dong, Eric Y. H. Park, Sarah Zipkowitz, Deepak A. Kaji, Ryan C. Thompson, Donjing Liu, , Michael S. Breen

This study compares A-to-I RNA editing in postmortem and living human brain tissues, revealing significant differences in editing levels and their association with cellular processes and neurological conditions.

Nature Communications · Jun 26, 2024Peer-reviewedGenetic & Genomic Medicine