Ryan C. Thompson

Genetic Associations with Temporal Modeling of Alzheimer's Disease Progression Supports a Novel Paradigm for Disease Risk

This paper uses temporal modeling of Alzheimer's disease progression with metabolomics data to identify novel genetic loci associated with disease speed, independent of traditional case-control associations.

A study of gene expression in the living human brain

This study compares gene expression in living and postmortem human brain tissue, finding significant differences that challenge the assumption that postmortem data accurately represents living brain gene expression.

Divergent landscapes of A-to-I editing in postmortem and living human brain

This study compares A-to-I RNA editing in postmortem and living human brain tissues, revealing significant differences in editing levels and their association with cellular processes and neurological conditions.

Characterizing cell type specific transcriptional differences between the living and postmortem human brain.

The paper compares gene expression differences between living and postmortem human brain samples using snRNA-seq and develops a model to account for these differences in analysis.