Comparative single-cell lineage bias in human and murine hematopoietic stem cells
Isaac Shamie, Meghan Bliss‐Moreau, Jamie Casey Lee, Ronald Mathieu, Harold M Hoffman, Bob Geng, Nathan E. Lewis, Yanfang Peipei Zhu, Ben A. Croker
The paper investigates lineage commitment bias in human and murine hematopoietic stem cells, finding that variation in myeloid and lymphoid engraftment is stochastic and not due to cell-intrinsic bias.
Haematologica · Jul 17, 2025Peer-reviewedGenomics