Vikram Singh

Anastrozole mediated modulation of mitochondrial activity by inhibition of mitochondrial permeability transition pore opening: An initial perspective

This study investigates anastrozole's effect on mitochondrial permeability transition pore (mPTP) by molecular docking, dynamics, and cell experiments, finding it more effective than cyclosporine A in inhibiting mPTP and improving mitochondrial function.

Characterizing circadian connectome of O. tenuiflorum using an integrated network theoretic framework

The paper identifies and characterizes core circadian clock proteins in Ocimum tenuiflorum using a hybrid network analysis approach.

Deciphering the multi-scale mechanisms of Tephrosia purpurea against polycystic ovarian syndrome (PCOS) and its major psychiatric comorbidities: studies from network-pharmacological perspective

This study evaluates the network pharmacology of Tephrosia purpurea phytochemicals against PCOS and its psychiatric comorbidities, identifying potential drug-like compounds and their molecular targets.

Genome-wide interologous interactome map (TeaGPIN) of Camellia sinensis

The paper constructs a genome-wide interologous protein-protein interaction network for Camellia sinensis, identifies key proteins, and explores its functional modules.

TulsiPIN: an interologous protein interactome of Ocimum tenuiflorum

The paper develops TulsiPIN, a genome-scale interologous protein-protein interaction network for Ocimum tenuiflorum, revealing 13,660 nodes and 327,409 interactions, and identifies 1,625 vital proteins.

Identification of multi-targeting and synergistic neuromodulators of epilepsy associated protein-targets in Ayurvedic herbs using network pharmacological approach

This study uses network pharmacology to identify anti-epileptic phytochemicals in Ayurvedic herbs and their interactions with epilepsy-related protein targets.

Construction and analysis of an interologous protein-protein interaction network of Camellia sinensisleaf (TeaLIPIN) from RNA-Seq datasets

The paper constructs an interologous protein-protein interaction network for Camellia sinensis using transcriptomic data and identifies bottleneck proteins with potential regulatory roles.

Piper longum: A review of its phytochemicals and their network pharmacological evaluation

This paper reviews the phytochemicals of Piper longum and evaluates their network pharmacological interactions with disease targets and pathways.