Author

Seema Kapoor

Lok Nayak Jai Prakash Narayan HospitalORCID 0000-0002-8974-1192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:variant calling· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mohammed FaruqiD· 2 shared Prashanth SuravajhalaiD· 2 shared Somesh KumariD· 2 shared Sunil Kumar PolipalliiD· 2 shared Alexej S. AbyzoviD· 1 shared Alice Lee· 1 shared Alissa M. D’GamaiD· 1 shared Andreas Schulze‐BonhageiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Mohammed FaruqORCID

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Author profile →

3 papers

Recent·Most cited

Anastrozole mediated modulation of mitochondrial activity by inhibition of mitochondrial permeability transition pore opening: An initial perspective

Somesh Kumar, Neha Choudhary, Mohammed Faruq, Arun Kumar, Ravindra Kumar Saran, Prem Kumar Indercanti, Vikram Singh, Haseena Sait, Sunita Jaitley, Martin Vališ, Kamil Kuča, Sunil Kumar Polipalli, Manoj Kumar, Tejveer Singh, Prashanth Suravajhala, , Seema Kapoor

This study investigates anastrozole's effect on mitochondrial permeability transition pore (mPTP) by molecular docking, dynamics, and cell experiments, finding it more effective than cyclosporine A in inhibiting mPTP and improving mitochondrial function.

Journal of Biomolecular Structure and Dynamics · Feb 23, 2023Peer-reviewedMolecular Biology

Comprehensive multiomic profiling of somatic mutations in malformations of cortical development

Changuk Chung, Xiaoxu Yang, Taejeong Bae, Keng Ioi Vong, Swapnil Mittal, Catharina Donkels, H. Westley Phillips, Zhen Li, Ashley P.L. Marsh, Martin W. Breuss, Laurel Ball, Camila Araújo Bernardino Garcia, Renee D. George, Jing Gu, Mingchu Xu, , Eduardo Maury

This study identifies 69 mutated genes in malformations of cortical development using multiomic profiling of 317 brain resections and single-cell sequencing.

Nature Genetics · Jan 12, 2023Peer-reviewedGenetics

Amplicon-based nanopore minion sequencing of patients with COVID-19 omicron variant from India

Somesh Kumar, Avinash Lomash, Mohammed Faruq, Oves Siddiqui, Suresh Kumar, Seema Kapoor, Prashanth Suravajhala, Sunil Kumar Polipalli, SCOG_MAMC_ LNH

The paper reports sequencing of the SARS-CoV-2 omicron variant in 13 Indian patients using Oxford Nanopore Minion technology to analyze 34 spike glycoprotein mutations.

medRxiv · Dec 27, 2021 · PreprintGenetic & Genomic Medicine