Author

Claus Ernst Moser

University of CopenhagenORCID 0000-0002-7664-8570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Oana CiofuiD· 2 shared Doaa HigazyiD· 1 shared Hengzhuang WangiD· 1 shared J. G. Coen van HasseltiD· 1 shared Jinqiu Yin· 1 shared Ke-Chuan WangiD· 1 shared Lene BayiD· 1 shared Linda B. S. AuliniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Oana CiofuORCID

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2 papers

Recent·Most cited

Pharmacodynamic modeling of colistin and imipenem against in vitro Pseudomonas aeruginosa biofilms

Yuchen Guo, Jinqiu Yin, Linda B. S. Aulin, Oana Ciofu, Claus Ernst Moser, Parth J. Upadhyay, Niels Høiby, Hengzhuang Wang, Tingjie Guo, J. G. Coen van Hasselt

This study develops a PK-PD model for imipenem and colistin against Pseudomonas aeruginosa biofilms to optimize clinical dosing schedules.

Biofilm · Aug 3, 2026Peer-reviewedPharmacology & Toxicology

Evolutionary Trajectories of Ciprofloxacin Resistance in P. aeruginosa Lung Biofilms: Mutation Dynamics, Metabolomic Shifts, and Collateral Sensitivity

Doaa Higazy, Ke-Chuan Wang, Lene Bay, Steen Seier Poulsen, Pernille Rose Jensen, Claus Moser, Oana Ciofu

This study tracks the evolution of ciprofloxacin resistance in P. aeruginosa biofilms, revealing metabolic shifts and collateral sensitivity to other antibiotics.

bioRxiv · May 19, 2026 · PreprintMicrobiology