Oana Ciofu

This study develops a PK-PD model for imipenem and colistin against Pseudomonas aeruginosa biofilms to optimize clinical dosing schedules.

This study tracks the evolution of ciprofloxacin resistance in P. aeruginosa biofilms, revealing metabolic shifts and collateral sensitivity to other antibiotics.

This study shows that serotype switching in Pseudomonas aeruginosa ST111 from O4 to O12 enhances adhesion, motility, and virulence in murine pneumonia.

This study shows that repeated phage exposure to P. aeruginosa biofilms reduces phage efficacy due to genetic changes that confer resistance and tolerance.