Author

Mohsen Sadeghi

Freie Universität BerlinORCID 0000-0002-7698-5630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1

Frequent Co-Authors

Burcu KepsutluiD· 1 shared Carolin KnappeiD· 1 shared Christian RosenmundiD· 1 shared Christoph A. DiebolderiD· 1 shared Frank NoéiD· 1 shared Gerd SchneideriD· 1 shared Helge EwersiD· 1 shared James G. McNallyiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Burcu KepsutluORCID

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2 papers

Recent·Most cited

Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons

Jana Kroll, Uljana Kravčenko, Mohsen Sadeghi, Christoph A. Diebolder, Lia Ivanov, Małgorzata Lubas, Thiemo Sprink, Magdalena Schacherl, Mikhail Kudryashev, Christian Rosenmund

This study visualizes synaptic vesicle fusion dynamics in mouse hippocampal neurons using cryo-electron tomography and simulations, revealing five fusion intermediates and a model of calcium-triggered fusion.

Nature Communications · Dec 13, 2025Peer-reviewedNeuroscience

3D-surface reconstruction of cellular cryo-soft X-ray microscopy tomograms using semi-supervised deep learning

Michael C. A. Dyhr, Mohsen Sadeghi, Ralitsa Moynova, Carolin Knappe, Burcu Kepsutlu, Stephan Werner, Gerd Schneider, James G. McNally, Frank Noé, Helge Ewers

This paper develops a semi-supervised deep learning pipeline for automated 3D segmentation of cryo-SXT tomograms, validated on mammalian cell ultrastructure and filopodia morphology.

bioRxiv · May 16, 2022 · PreprintBioinformatics