Jana Kroll

This paper shows that presynaptic filopodia, driven by activity, calcium, and actin, physically modulate membrane mechanics to enhance synchronous neurotransmission and contribute to seizure generation.

This study visualizes synaptic vesicle fusion dynamics in mouse hippocampal neurons using cryo-electron tomography and simulations, revealing five fusion intermediates and a model of calcium-triggered fusion.

This study uses cryo-electron tomography to describe the molecular architecture and structural heterogeneity of individual synaptic vesicles in mouse brains and cultured neurons.

The paper identifies specific amino acid residues in the complexin N-terminus that differentially affect spontaneous and evoked neurotransmitter release in hippocampal neurons.

The paper shows that 30% of inner hair cells in the rodent cochlea form electrochemical mini-syncytia through membrane fusion, enhancing sound encoding sensitivity and reliability.

This study shows endophilin-A1 and A2 regulate exocytosis of neurosecretory vesicles by controlling recruitment, priming, and fusion, independent of their endocytic roles.