Mikhail Kudryashev

This study uses cryo-electron tomography to reveal the structure of EHD2 filaments on curved membranes, showing how they stabilize caveolar necks and their role in cellular dynamics.

The paper integrates structural and proteomic methods to characterize the protein organization of a giant virus, identifying sub-compartments and membrane protein topologies.

The paper presents cryo-EM structures of the naked mole-rat ribosome, revealing a stabilized split 28S rRNA and its structural context.

This study shows HRS forms 2D condensates that drive flat clathrin lattice assembly on endosomes, with cholesterol enhancing this process.

DeBCR improves microscopy image quality through physics-informed deep learning, outperforming existing models in denoising, deblurring, and optical deconvolution across light microscopy and cryo-ET.

This study visualizes synaptic vesicle fusion dynamics in mouse hippocampal neurons using cryo-electron tomography and simulations, revealing five fusion intermediates and a model of calcium-triggered fusion.

This study uses cryo-electron tomography to describe the molecular architecture and structural heterogeneity of individual synaptic vesicles in mouse brains and cultured neurons.