Author

Melissa B. DeLeeuw

Vanderbilt University Medical CenterORCID 0000-0002-7700-016XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Genevieve X Hunn· 1 shared Jing‐Qiong KangiD· 1 shared Juexin WangiD· 1 shared Kirill A. ZavaliniD· 1 shared Li Ma· 1 shared Ria S EdaiD· 1 shared Wangzhen SheniD· 1 shared Ziang (Debbie) Song· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Genevieve X Hunn

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1 paper

Recent·Most cited

4-Phenylbutyrate Rescue in GABRA1 Variants Associated with Developmental Epileptic Encephalopathies: from Cell and Mouse Models to Human

Ziang (Debbie) Song, Kirill A. Zavalin, Wangzhen Shen, Melissa B. DeLeeuw, Genevieve X Hunn, Ria S Eda, Li Ma, Juexin Wang, Jing‐Qiong Kang

This study tests the therapeutic effect of 4-phenylbutyrate (PBA) on GABRA1 variants associated with developmental epileptic encephalopathies using cell and mouse models, showing improved receptor expression and function.

Cells · Jul 24, 2026Peer-reviewedNeuroscience