PhysiologybioRxivPreprint
Muscle March5 restrains an ATF4-GDF15 endocrine stress axis that modulates feeding and body composition
Guixing Ma, Yuehua Chen, Siyuan Cheng…·Huiling Cao
This study identifies March5 as a muscle proteostatic checkpoint that limits ATF4-dependent GDF15 production, linking muscle health to feeding and body composition.
DOI 10.64898/2026.07.07.737120