Author

Hanna Sothers

University of Alabama at BirminghamORCID 0000-0002-7757-1843Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Merry‐Lynn McDonaldiD· 2 shared Anna Elizabeth Thalacker‐MerceriD· 1 shared Bitota K Lukusa-SawalenaiD· 1 shared David K. CrossmaniD· 1 shared Harry B. RossiteriD· 1 shared James Michael WellsiD· 1 shared Joe W. ChilesiD· 1 shared Kaleen M. LaviniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Merry‐Lynn McDonaldORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 4, 2026

Distinct Myogenic Stages Recapitulate Transcriptomic Networks of Skeletal Muscle in COPD Cachexia

Hanna Sothers, Bitota K Lukusa-Sawalena, Kaleen M. Lavin…·Merry‐Lynn McDonald

The paper identifies transcriptomic signatures of COPD and COPD-cachexia in skeletal muscle and shows they are preserved across differentiation stages in human muscle-derived cultures.

DOI 10.64898/2025.12.03.692216

humanbulk RNA-seq

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BioinformaticsJournal of Cachexia Sarcopenia and MusclePeer-reviewedJul 10, 2025

Late-Stage Skeletal Muscle Transcriptome in Duchenne muscular dystrophy shows a BMP4-Induced Molecular Signature

Hanna Sothers, Xianzhen Hu, David K. Crossman…·Michael A. Lopez

The paper identifies a BMP4-induced molecular signature in late-stage DMD skeletal muscle by comparing transcriptomes of DMD patients and BMP4-stimulated cells.

8 citations

humanbulk RNA-seq

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