Author

Joe W. Chiles

University of Alabama at BirminghamORCID 0000-0002-9935-6319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Merry‐Lynn McDonaldiD· 2 shared Alison Rocco· 1 shared Anna Elizabeth Thalacker‐MerceriD· 1 shared Ashwathy Nair· 1 shared Ava C. WilsoniD· 1 shared Bitota K Lukusa-SawalenaiD· 1 shared Cynthia J. BrowniD· 1 shared Hanna SothersiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Merry‐Lynn McDonaldORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Distinct Myogenic Stages Recapitulate Transcriptomic Networks of Skeletal Muscle in COPD Cachexia

Hanna Sothers, Bitota K Lukusa-Sawalena, Kaleen M. Lavin, Wenxia Ma, Joe W. Chiles, Richard H. Casaburi, Rakesh P. Patel, James Michael Wells, Mohamed Kazamel, Harry B. Rossiter, Anna Elizabeth Thalacker‐Mercer, Merry‐Lynn McDonald

The paper identifies transcriptomic signatures of COPD and COPD-cachexia in skeletal muscle and shows they are preserved across differentiation stages in human muscle-derived cultures.

bioRxiv · Aug 4, 2026 · PreprintGenetics

Novel Genetic Loci Associated with Osteoarthritis in Multi-Ancestry Analyses in 484,374 Participants from MVP and the UK Biobank.

Merry‐Lynn McDonald, Preeti Lakshman Kumar, Vinodh Srinivasasainagendra, Ashwathy Nair, Alison Rocco, Ava C. Wilson, Joe W. Chiles, Joshua Richman, Sarah A. Pinson, Richard A. Dennis, Vivek S. Jagadale, Cynthia J. Brown, Saiju Pyarajan, Hemant K. Tiwari, Marcas M. Bamman, , the VA Million Veteran Program

The paper identifies 10 novel genetic loci associated with osteoarthritis in multi-ancestry analyses of 484,374 participants from MVP and UK Biobank, with some regions robust across populations.

medRxiv · Jun 14, 2022 · PreprintGenetic & Genomic Medicine