Author

Mohamed Ghafoor

University of ManchesterORCID 0000-0002-7757-3224Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Magnus RattrayiD· 3 shared James E ParkinsoniD· 2 shared Sokratia GeorgakaiD· 2 shared Tara E. SutherlandiD· 2 shared Amin AliiD· 1 shared Diego Fernando SancheziD· 1 shared Elliot J. JokliD· 1 shared Hannah E TompkinsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBioinformatics

Magnus RattrayORCID

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3 papers

Recent·Most cited

ImmunologyMolecular Systems BiologyPeer-reviewedJul 20, 2026

Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation.

James E Parkinson, Morgan Bryant, Mohamed Ghafoor…·Tara E. Sutherland

The paper uses imaging mass cytometry to analyze ECM composition in mouse models of allergic airway inflammation, identifying distinct matrix environments associated with different cell types and tissue regions.

4 citations

mouseimaging

BioinformaticsbioRxivPreprintJun 4, 2025

Mantpy: a framework for extracellular matrix analysis in spatial proteomics

Mohamed Ghafoor, James E Parkinson, Thao Pham…·Magnus Rattray

Mantpy is a framework for analyzing the extracellular matrix in spatial proteomics by representing it as spatial graphs and integrating it with cell data for joint analysis.

DOI 10.1101/2025.06.04.657781

mousespatial transcriptomics

BioinformaticsNucleic Acids ResearchPeer-reviewedMar 20, 2025

CellPie: a scalable spatial transcriptomics factor discovery method via joint non-negative matrix factorization

Sokratia Georgaka, William Geraint Morgans, Qian Zhao…·Magnus Rattray

CellPie is a fast, unsupervised method for factor discovery in spatial transcriptomics using joint non-negative matrix factorization, showing improved performance on human cancer datasets.

13 citations

humanspatial transcriptomics