Author

Sumanth Reddy Nakkireddy

Vanderbilt University Medical CenterORCID 0000-0002-7771-6782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Anthony GrichukiD· 1 shared Barrett L. Updegraff· 1 shared Bret M. EversiD· 1 shared Hari Shankar SuniliD· 1 shared Indhumathy SubramaniyaniD· 1 shared Isabel BarnfatheriD· 1 shared Jean Rene V. ClemenceauiD· 1 shared Jingfei ZhuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anthony GrichukORCID

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1 paper

Recent·Most cited

Transmembrane Serine Protease TMPRSS11B promotes an acidified tumor microenvironment and immune suppression in lung squamous cell carcinoma

Hari Shankar Sunil, Jean Rene V. Clemenceau, Isabel Barnfather, Sumanth Reddy Nakkireddy, Anthony Grichuk, Luke Izzo, Bret M. Evers, Lisa B. Thomas, Indhumathy Subramaniyan, Lan Li, William T. Putnam, Jingfei Zhu, Barrett L. Updegraff, John Dorrance Minna, Ralph J. DeBerardinis, , Kathryn A. O’Donnell

This study shows that TMPRSS11B promotes an acidified and immunosuppressive tumor microenvironment in lung squamous cell carcinoma, suggesting it as a therapeutic target.

bioRxiv · Apr 1, 2025 · PreprintCancer Biology