Author

Marianna Langione

University of FlorenceORCID 0000-0002-7783-2177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alberto MagiiD· 1 shared Beatrice ScelliniiD· 1 shared Camilla OliantiiD· 1 shared Cecilia FerrantiniiD· 1 shared Chiara TesiiD· 1 shared Corrado PoggesiiD· 1 shared Elema MartelliiD· 1 shared Elisabetta CerbaiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Alberto MagiORCID

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1 paper

Recent·Most cited

Long-term mavacamten exposure reduces force and sarcomere density in a hiPSC model of hypertrophic cardiomyopathy

Marianna Langione, Lucrezia Giammarino, Roberto Semeraro, Beatrice Scellini, Sonette Steczina, Valentina Spinelli, Elema Martelli, Irma Della Corte, Camilla Olianti, Alberto Magi, Leonardo Sacconi, Elisabetta Cerbai, Michael Regnier, Iacopo Olivotto, Chiara Tesi, , Josè Manuel Pioner

This study examines the long-term effects of mavacamten on sarcomere structure and function in hiPSC-derived cardiomyocytes from HCM patients, finding a biphasic reduction in force and structural remodeling.

Cardiovascular Research · Jul 13, 2026Peer-reviewedPhysiology