Author

Chiara Tesi

University of FlorenceORCID 0000-0002-1111-1473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Beatrice ScelliniiD· 3 shared Corrado PoggesiiD· 3 shared Cecilia FerrantiniiD· 2 shared Leonardo SacconiiD· 2 shared Michael RegnieriD· 2 shared Nicoletta PiroddiiD· 2 shared Alberto MagiiD· 1 shared Camilla OliantiiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersPhysiology

Beatrice ScelliniORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Probing relaxed myosin states in hypertrophic cardiomyopathy by second harmonic-generation microscopy

Giulia Arecchi, Marica Dente, Weikang Ma, Beatrice Scellini, Nicoletta Piroddi, Marina Scardigli, Jingyuan Yu, Jing Zhao, Riccardo Cicchi, Ryo Kinegawa, Caroline Muellenbroich, Francesco Sera, Corrado Poggesi, Cecilia Ferrantini, Thomas C. Irving, , Chiara Tesi

This paper uses polarized second-harmonic generation microscopy to analyze myosin states in hypertrophic cardiomyopathy, showing increased ON state fraction in mutated tissue.

eLife · Aug 17, 2026Peer-reviewedPhysiology

Long-term mavacamten exposure reduces force and sarcomere density in a hiPSC model of hypertrophic cardiomyopathy

Marianna Langione, Lucrezia Giammarino, Roberto Semeraro, Beatrice Scellini, Sonette Steczina, Valentina Spinelli, Elema Martelli, Irma Della Corte, Camilla Olianti, Alberto Magi, Leonardo Sacconi, Elisabetta Cerbai, Michael Regnier, Iacopo Olivotto, Chiara Tesi, , Josè Manuel Pioner

This study examines the long-term effects of mavacamten on sarcomere structure and function in hiPSC-derived cardiomyocytes from HCM patients, finding a biphasic reduction in force and structural remodeling.

Cardiovascular Research · Jul 13, 2026Peer-reviewedPhysiology

Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities

Giuseppina Mastrototaro, Pierluigi Carullo, Jianlin Zhang, Beatrice Scellini, Nicoletta Piroddi, Simona Nemska, Maria Carmela Filomena, Simone Serio, Carol A. Otey, Chiara Tesi, Fabian C. Emrich, Wolfgang Albrecht Linke, Corrado Poggesi, Simona Boncompagni, Marie‐Louise Bang

This study shows that ablating PALLD in adult hearts causes dilated cardiomyopathy with intercalated disc abnormalities and fibrosis, suggesting PALLD's essential role in cardiac function.

eLife · Mar 16, 2023Peer-reviewedMolecular Biology