Leonie von Berlin

The paper develops ML models to predict antimicrobial activity of small molecules using a knowledge graph, achieving 75.9% accuracy in identifying active compounds.

The paper identifies heritable transcriptional diversity within cell types by studying clonal human lymphocytes and mouse brain cells, showing clone-specific chromatin accessibility leads to distinct gene expression.

This study uses single-cell and spatial transcriptomics to reveal clonal relationships and cell types in the mouse brain, showing fate-restricted progenitor cells and microglia origins.