Olga Genilloud

This study identifies a novel family of bacitracin-type antibiotics, paenitracins, produced by Paenibacillus species using a metabolomics-genomics workflow.

This study develops quenched activity-based probes (qABPs) using β-lactam cores to selectively detect human neutrophil elastase in live cells.

This study identifies ENOblock, an anticancer drug, as a novel antibiotic targeting Acinetobacter baumannii enolase, showing synergy with colistin and efficacy in vivo.

The paper presents a morphological profiling dataset of EU-OPENSCREEN bioactive compounds across multiple imaging sites and cell lines, validated for robustness and used to map profiles to activity and toxicity.

The paper develops ML models to predict antimicrobial activity of small molecules using a knowledge graph, achieving 75.9% accuracy in identifying active compounds.

The paper identifies and clones the cacaoidin biosynthetic gene cluster from Streptomyces cacaoi CA-170360 and describes its heterologous expression.

The paper demonstrates the heterologous expression of two cyclic pentapeptide families from Streptomyces cacaoi CA-170360, showing their biosynthesis by two nonribosomal peptide synthetases and a Penicillin Binding Protein enzyme.